Objectives: To determine the frequency of specific causes of urinary tract infection among women of reproductive age in Vukovar-Srijem County. To examine the relationship between the patients' sociodemographic characteristics and the referraal diagnosis of the patients with the urine test results. Study design: A cross-sectional study conducted between March 1, 2019, and June 1, 2019, at the Microbiology Service of the Public Health Institute of Vukovar-Srijem County. Participants and methods: The study included women of reproductive age from 18 to 50 years old who underwent microbiological analysis of urine at the Microbiology Service of the Public Health Institute of Vukovar-Srijem County whose samples were positive for IMS after microbiological tretment. Results: The study included 266 women of reproductive age. IMS was found in 38,0 % of patients, and in 62,0 %, the results of the microbiological examination of urine were negative. 45,1 % of patients were from the urban area and 54,9 % were from the rural area. The most common agent was E. coli, which was found in 14,8 % of patients. Conclusion: A study conducted in Vukovar-Srijem County among women of reproductive age from 18 to 50 years old, found an IMS incidence of 38,0 %. The most common cause of IMS was E. coli, in 46,5 % of cases. Inflammation of the bladder (N30) is the most common referral diagnosis for subjects whose urine culture is positive. There was no statistically significant difference in the incidence of the causative agent in relation to the age group. Given the relatively small number of subjects, no statistical significance was found in the incidence of IMS in the elderly subjects and subjects from rural areas.