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master's thesis
Učinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika
2020. urn:nbn:hr:152:371383
Pavlović, Ana
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Pavlović, A. (2020). Učinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:371383

Pavlović, Ana. "Učinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2020. https://urn.nsk.hr/urn:nbn:hr:152:371383

Pavlović, Ana. "Učinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2020. https://urn.nsk.hr/urn:nbn:hr:152:371383

Pavlović, A. (2020). 'Učinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 20 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:371383

Pavlović A. Učinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2020 [cited 2024 November 20] Available at: https://urn.nsk.hr/urn:nbn:hr:152:371383

A. Pavlović, "Učinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:152:371383

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TitleUčinak dijete s povećanim unosom n-3 polinezasićenih masnih kiselina na udio Foxp3 regulatornih T limfocita u perifernoj krvi zdravih mladih ispitanika
Title (english)The effect of increased dietary intake of n-3 PUFAs on the Foxp3 regulatory T-cell frequencies in the peripheral blood of healthy young subjects
AuthorAna Pavlović
MentorMartina Mihalj (mentor)
Committee memberInes Drenjančević (predsjednik povjerenstva)
Committee memberAna Stupin (član povjerenstva)
Committee memberMartina Mihalj (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2020-09-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract
Cilj: Odrediti udjele regulatornih T-limfocita u krvi mladih zdravih ispitanika nakon konzumacije funkcionalne hrane obogaćene n-3 polinezasićenim masnim kiselinama (3 kokošja jaja dnevno). Ustroj studije: Studija je ustrojena kao istraživanje parova. Materijali i metode: 40 mladih, zdravih, sedentarnih ispitanika obaju spolova, od 19 do 28 godina podijeljeno je u dvije skupine: kontrolna (ispitanici koji su 3 tjedna svakodnevno konzumirali 3 standardna kokošja jaja; 249 mg n-3 PUFA dnevno) i omega-3 skupina (ispitanici koji su 3 tjedna svakodnevno konzumirali 3 kokošja jaja obogaćena n-3 polinezasićenim masnim kiselinama; 1053 g n-3 PUFA dnevno). Udio regulatornih T-limfocita određen je iz pune krvi ispitanika metodom protočne citometrije. Rezultati: Udio regulatornih CD25+Foxp3+ T-limfocita statistički je značajno niži u obje ispitivane skupine, u kontrolnoj skupini nakon povećanog unosa standardnih kokošjih jaja te u omega-3 skupini nakon povećanog unosa n-3 PUFA obogaćenih kokošjih jaja. Zaključak: Povećan unos kokošjih jaja, neovisno o dodatku n-3 polinezasićenih masnih kiselina, kod zdravih mladih ispitanika dovodi do pada udjela regulatornih CD25+Foxp3+ T-limfocita u perifernoj krvi.
Abstract (english)
Objectives: The aim of this study was to determine the level of regulatory T lymphocytes in the blood of young healthy individuals after consumption of functional food enriched with n-3 polyunsaturated fatty acids (3 hen eggs per day). Study Design: case-control study Material and Methods: Forty young, healthy, sedentary individuals, both male and female, aged 19 to 28 were divided into two groups: control group (individuals who consumed 3 standard hen eggs per day for 3 weeks; 249 mg n-3 PUFA/day) and omega-3 group (individuals who consumed 3 hen eggs enriched with n-3 polyunsaturated fatty acids per day for 3 weeks; 1053 g n-3 PUFA/day). The level of regulatory T lymphocytes was determined from the individual's whole blood by flow cytometry. Results: The proportion of regulatory CD25+Foxp3+ T lymphocytes was statistically significantly lower in both groups, the control group after increased intake of regular hen eggs and in the omega-3 group after diet with increased intake of n-3 PUFA enriched hen eggs. Conclusion: Increased intake of hen eggs, regardless of the n-3 polyunsaturated fatty acids addition, in healthy young individuals leads to a decrease in the proportion of regulatory CD25+Foxp3+ T lymphocytes.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:371383
Study programmeTitle: University graduate study
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra medicinsko laboratorijske dijagnostike (magistar/magistra medicinsko laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2020-12-18 08:40:58