Abstract | Cilj: Utvrditi prevalenciju spolne disfunkcije (SD) u populaciji žena s nadomještanjem bubrežne funkcije (NBF) i u ovisnosti o vrsti NBF-a kroničnom hemodijalizom (CHD, od engl. chronic hemodialysis) ili bubrežnom presadbom (TX, od engl. transplantation), SD u ovisnosti o slici o sebi, razini depresivnosti i tjeskobe i o komorbiditetu. Ispitanici i postupci: Ispitane su 54 bolesnice liječene CHD-om, 53 liječene TX-om i 90 zdravih kontrola. Ispitanice su ispunjavale sociodemografski upitnik; upitnik o depresivnosti, PHQ9, od engl. The Patient Health Questionnaire; upitnik o tjeskobi, GAD7, od engl. Generalized Anxiety Disorder-7; upitnik -indeks ženske spolne funkcije, FSFI, od engl. Female Sexual Function Indeks; upitnik slike o svome tijelu, BIS, od engl. Body Image Scale te indeks Ifudu o komorbiditetima. Statistička raščlamba učinjena je pomoću programa IBM SPSS Statistics, razina značajnosti P < 0,05. Rezultati: SD je nađena u 90 % bolesnica na CHD-u, postotak u podskupini koje su u vezi u više od 50 %. Prevalencija je bila značajno niža za kontrole (12,5 %) i skupinu TX (44,44 %). Ispitanice skupine CHD pokazale su više razine depresivnosti od ostalih skupina. Nije bilo značajnih razlika u tjeskobi među skupinama. Lošija slika o sebi nađena je u skupini CHD u odnosu na zdrave kontrole. SD je bila češća u žena starije dobi, onih s većim brojem djece, postojanjem depresivnosti i niskim stupnjem obrazovanja. Isti čimbenici utjecali su na lošiju sliku o sebi. Pronađene su statistički značajne razlike u obilježjima SD-a u ispitanica na dijalizi u odnosu na kontrole, nije bilo značajne razlike između skupine TX i kontrola. Komorbiditeti su pozitivno korelirali s FSFI-jem u skupini CHD. Zaključak: Velik udio bolesnica s NBF-om ima SD, one liječene CHD-om češće nego dobno prilagođene kontrole i bolesnice skupine TX. Skupina TX imala je bolju spolnu funkciju od CHD skupine, dok nije bilo značajnih razlika između zdravih kontrola i skupine TX. Slika o sebi bila je niža u skupini CHD u odnosu na kontrole. Razine depresivnosti bile su više u skupini CHD u odnosu na druge skupine. Potrebne su daljnje analize ove populacije radi razvijanja dijagnostike i liječenja SD-a. |
Abstract (english) | Aim: To determine the prevalence of sexual dysfunction (SD) in the population of women with renal replacement therapy (RRT) and in relation to the type of therapy: CHD (chronic hemodialysis) or TX (transplantation) and SD in relation to body image, levels of depression, anxiety and comorbidities. Methods: A total of 54 CHD and 53 TX patients as well as 90 healthy controls were questionned using a sociodemographic questionnaire, PHQ9 (The Patient Health Questionnaire), GAD7 (Generalized Anxiety Disorder - 7), FSFI (Female Sexual Function Index), BIS (Body Image Scale) and Ifudu Index (about comorbidities). Statistical analysis was performed using the software program a IBM SPSS Statistics. P < 0.05 was considered statistically significant. Results: Out of the dialysis patients, 90 % filled the criteria for SD, or 50 % of those women who were in a relationship. The prevalence was lower for healthy controls (12.5 %) and TX patients (44.44 %). CHD patients showed higher levels of depression than the other two groups. No significant differences in anxiety were observed. Lower Body Image was found in the CHD group when compared to controls. SD was more prevalent in older women, those with more children, depression, and lower levels of education. The same parameters were associated with a lower body image. Significant differences in SD were noticed between the dialysis and healhy control group, while no differences were observed between the transplant and healthy control group. Comorbidies correlated positively with FSFI in CHD group. Conclusion: A large proportion of patients with RRT had SD, which was more prominent in CHD group when compared to the TX and control groups. TX patients had better sexual function than those on dialysis, while no significant differences were observed between healthy controls and TX. Body image was lower in the CHD group when compared to controls, while levels of depression were more pronounced in the CHD group when compared to the other groups. More research is needed in this population in order to develop proper diagnostic and therapeutic measures for treating SD. |