| Abstract | Cilj istraživanja: Primarni cilj istraživanja bio je utvrditi postoji li povezanost indeksa tjelesne mase (ITM) i stupnja težine opstruktivne apneje u spavanju (OSA). Ostali ciljevi bili su ispitati utjecaj ITM-a na dnevnu pospanost bolesnika s OSA-om, zatim ispitati povezanost ITM-a sa stupnjem desaturacije periferne krvi kisikom te ispitati postoji li utjecaj ITM-a na učestalost pojave hrkanja tijekom spavanja. Nacrt studije: Istraživanje je ustrojeno kao presječno istraživanje s povijesnim podacima Bolesnici i metode: U istraživanju je sudjelovalo 70 ispitanika, kojima je polisomnografijom dijagnosticirana OSA i postavljen stupanj težine bolesti putem apneja/hipopneja indeksa (AHI). U istraživanju su korišteni demografski podaci pacijenata (dob, spol, visina, masa, ITM, zaposlenost), podaci o konzumaciji alkohola, pušenju cigareta, hipertenziji i dijabetesu, rezultat Epworthove ljestvice, rezultat STOP-BANG upitnika te polisomnografski parametri (poput broja i trajanja apneja i hipopneja, AHI, saturacije s najnižom desaturacijom, te broj epizoda i trajanje hrkanja). Rezultati: U istraživanju je sudjelovalo 53 muškarca i 17 žena. Analizom polisomnografija potvrđeno je 49 ispitanika s teškom OSA-om, od kojih je 40 pretilo (82 %). 12 od 13 ukupno pretilih trećeg stupnja pati od teške OSA-e. Rast rezultata STOP-BANG upitnika korelira sa stupnjem OSA-e. Značajno je snižena saturacija kod pretilih ispitanika, a hrkanje i udio hrkanja u spavanju znatno pojačani. Zaključak: Temeljem rezultata istraživanja uočena je povezanost pretilosti sa stupnjem OSA-e i porastom AHI-a, zatim povezanost pretilosti sa padom srednje saturacije i najniže desaturacije te značajan porast broja epizoda hrkanja, trajanja hrkanja i njegovog udjela u spavanju s porastom ITM-a. Značajan utjecaj pretilosti na dnevnu pospanost nije zabilježen. |
| Abstract (english) | Title: Relationship between body mass index and severity of obstructive sleep apnoea Objectives: The primary objective of this study was to determine whether there was an association between body mass index (BMI) and the severity of obstructive sleep apnoea (OSA). Other objectives were to investigate the effect of BMI on increased daytime sleepiness in patients, to investigate the relationship between BMI and the severity of oxygen desaturation, and finally to investigate whether BMI is related to snoring frequency. Study Design: This is a cross-sectional study with historic data Patients and Methods: In this research 70 patients were involved, all who were diagnosed with OSA using polysomnography (PSG) and were determined the severity of OSA, based on the AHI index. The study used demographic data of patients (such as age, sex, height, weight, BMI, employment), data of alcohol consumption, cigarette smoking, hypertension and diabetes, the result of the Epworth scale, the result of STOP-BANG questionnaire and polysomnographic parameters (such as the number and duration of apnoeas and hypopnoeas, AHI, saturation with the lowest desaturation, and the number of episodes and duration of snoring). Results: The study involved 53 men and 17 women. Polysomnography analysis confirmed 49 subjects with severe OSA, of whom 40 were obese (82%). 12 out of 13 third-degree obese people suffer from severe OSA. The growth of the results of the STOP-BANG questionnaire correlates with the degree of OSA. Saturation was significantly reduced in obese subjects, and snoring and the percentage of snoring in sleep were significantly increased. Conclusion: Based on the results of the study, the association of obesity with the degree of OSA and the increase in AHI was confirmed, followed by the association of obesity with a decrease in mean saturation and lowest desaturation and a significant increase in snoring episodes, snoring duration and its percentage in sleep with BMI. Significant effects of obesity on daytime sleepiness have not been reported. Keywords: |
