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master's thesis
Razlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome
2023. urn:nbn:hr:152:323334
Papišta, Dino
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Papišta, D. (2023). Razlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:323334

Papišta, Dino. "Razlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2023. https://urn.nsk.hr/urn:nbn:hr:152:323334

Papišta, Dino. "Razlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2023. https://urn.nsk.hr/urn:nbn:hr:152:323334

Papišta, D. (2023). 'Razlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 25 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:323334

Papišta D. Razlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2023 [cited 2024 November 25] Available at: https://urn.nsk.hr/urn:nbn:hr:152:323334

D. Papišta, "Razlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:152:323334

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Metadata
TitleRazlika DaTSPECT-a kod bolesnika s Parkinsonovom bolesti u odnosu na Parkinson plus sindrome
Title (english)Difference in DAT SPECT in patients with Parkinson`s disease in relation to Parkinson plus syndromes
AuthorDino Papišta
MentorSvetlana Tomić (mentor)
Committee memberMarija Heffer (predsjednik povjerenstva)
Committee memberDarija Šnajder Mujkić (član povjerenstva)
Committee memberSvetlana Tomić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2023-09-19, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract
Ciljevi istraživanja. Ispitati razliku u simetriji i stupnju smanjenoga vezivanja radioizotopa u putamenu i nucleusu caudatusu te povezanosti smanjenog vezivanja u ovisnosti o duljini trajanja simptoma u bolesnika oboljelih od Parkinsonove bolesti i Parkinson plus sindroma. Nacrt studije. Retrospektivna studija. Ispitanici i metode. Istraživanje se provelo na 43 bolesnika s dijagnosticiranom Parkinsonovom bolesti ili s dijagnosticiranim Parkinson plus sindromom koji se liječe i kontroliraju u Klinici za neurologiju u sastavu Kliničkog bolničkog centra Osijek. Podatci o bolesnicima i nalazu DaTSPECT-a prikupljeni su iz bolničkog informatičkog sustava na temelju registra bolesnika. Rezultati. Značajno su niže vrijednosti vezivanja radioizotopa u striatumu, nucleusu caudatusu i putamenu u bolesnika oboljelih od Parkinson plus sindroma u odnosu na oboljele od Parkinsonove bolesti, dok se značajno ne razlikuju apsolutne razlike lijeve i desne strane obje ispitivane skupine. Nije uočena povezanost duljine trajanja bolesti sa stupnjem oštećenja bazalnih ganglija. Zaključak. Uočena je značajna razlika u smanjenome vezivanju radioizotopa u striatumu, nucleusu caudatusu i putamenu u bolesnika oboljelih od Parkinson plus sindroma u odnosu na oboljele od Parkinsonove bolesti. Nije uočena razlika u simetriji lijeve i desne strane u obje skupine kao niti povezanost s duljinom trajanja simptoma.
Abstract (english)
Difference in DaTSPECT in patients with Parkinson's disease in relation to Parkinson plus syndrome Objectives. To examine the difference in the symmetry and reduction of radioisotope binding in the putamen and the caudate nucleus and it`s correlation with the duration of symptoms in patients with Parkinson's disease and with Parkinson plus syndrome. Study design. Retrospective study. Participants and methods. The research was conducted on 43 patients diagnosed with Parkinson's disease or diagnosed with Parkinson's plus syndrome who are treated and monitored at the Clinic for Neurology within the Clinical Hospital Center in Osijek. Patient data and DaTSPECT findings were collected from the hospital information system based on the patient register. Results. Significantly lower radioisotope binding values were observed in the striatum, caudate nucleus and putamen in patients with Parkinson's plus syndrome compared to patients with Parkinson's disease, while the absolute differences between the left and right sides of both examined groups were not significantly different. No correlation was observed between symptoms duration and basal ganglia level of destruction. Conclusion. A significant difference was observed in reduced binding of radioisotope in the striatum, caudate nucleus and putamen in patients with Parkinson's plus syndrome compared to patients with Parkinson's disease. No difference was observed in the symmetry of the left and right sides in both groups, neither correlation with symptoms duration.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:323334
Study programmeTitle: University Graduate Studies
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-12 13:37:24