Objectives: The main aim of this research was to question if there are differences in pain intensity, pain perception and the effect of pain on changes in life decisions among the patients with headache and cervical pain syndrome before and after physiotherapy and acupuncture, and to question if there are differences in the data obtained before and after therapy. Study design: The study is designed as a cross-sectional study. Participants and methods: The research included 34 participants who were treated with acupuncture and physiotherapy for headache and cervical pain syndrome in addition to pharmacotherapy at the Department of pain menangment of KBC Osijek. Before and two weeks after the therapy, the participants filled in four anonymous questionnares that examined personal data, assesment and perception of pain (PDQ), acceptance of pain (CPAQ) and symptoms of anxiety and depression (DASS-14). Results: The majority of participants were female between the ages of 45 and 60, and the most common diagnosis was cervicobrachial syndrome. All participants underwent acupuncture therapy, and TENS was the most common physiotherapy method. There was a significant reduction in pain intensity and the level of neuropathic pain component after the therapy. Also, no difference was observed in the acceptance of pain and the presence of symptoms of anxiety and depression before and after the therapy. Conclusion: Two weeks after acupuncture and physiotherapy, the participants experienced a significant reduction in pain intensity and the level of neuropathic pain component. In contrast, there was no significant difference in the acceptance of pain and the presence of anxiety and depressive symptoms in the period before and after the therapy.