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master's thesis
Promjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka
2017. urn:nbn:hr:152:881063
Silović, Josip
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Silović, J. (2017). Promjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:881063

Silović, Josip. "Promjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:881063

Silović, Josip. "Promjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:881063

Silović, J. (2017). 'Promjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 24 April 2025, https://urn.nsk.hr/urn:nbn:hr:152:881063

Silović J. Promjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2017 [cited 2025 April 24] Available at: https://urn.nsk.hr/urn:nbn:hr:152:881063

J. Silović, "Promjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:152:881063

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TitlePromjene plućnog i perifernog vaskularnog otpora kod bolesnika nakon aortokoronarnog premoštenja ili zamjene zalistaka
Title (english)Changes of pulmonary and peripheral vascular resistance in the patients after coronary artery bypass or valve replacement
AuthorJosip Silović
MentorSlavica Kvolik (mentor)
Committee memberIvan Radoš (predsjednik povjerenstva)
Committee memberVesna Ilakovac (član povjerenstva)
Committee memberSlavica Kvolik (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2017-06-27, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
Ciljevi istraživanja: Izmjeriti razlike u demografskim pokazateljima, usporediti vrijednosti plućnog i perifernog vaskularnog otpora te vrijednosti troponina kod bolesnika podvrgnutih operaciji aortokoronarnog premoštenja, zamjeni zalistaka ili objema operacijama. Nacrt studije: Retrospektivno istraživanje Materijal i metode: U istraživanje je bilo uključeno 108 kardiokirurških bolesnika operiranih od 4. siječnja 2016. do 25. svibnja 2016. kojima su analizirane povijesti bolesti i ispisi hemodinamskih vrijednosti. Bolesnici su bili podijeljeni u tri skupine s obzirom na operacijski zahvat. U ispitanim skupinama uspoređeni su demografski pokazatelji, laboratorijski nalazi i hemodinamske vrijednosti. Svi podatci analizirani su uporabom t-testa i χ2 test, Fisherova egzaktnog testa, ANOVA testa te Pearsonove korelacije. Rezultati: Ispitivane skupine nisu se razlikovale po dobi i spolu. Najčešći komorbiditet u svim skupinama bila je hipertenzija (94,44 %). Prosječne vrijednosti indeksa tjelesne mase bile su veće od 29. Vrijednosti eritrocita (E), hemoglobina (Hgb) i trombocita (Trc) bile su najmanje kod bolesnika kojima je učinjena operacija valvule (E = 3,42, Hgb = 102,75, Trc = 110,34). Najviše vrijednosti troponina imala je skupina bolesnika kojima su učinjene obje operacija, a najniže kojima je učinjeno aortokoronarno premoštenje. Postoji pozitivna povezanost između troponina, plućnog i perifernog vaskularnog otpora, troponina i srednjeg tlaka u plućnoj arteriji, a negativna između troponina, udarnog i minutnog volumena (p<0,05 za sve usporedbe). Zaključak: Infarkt miokarda, diabetes, poremećaji lipida i angina pectoris manje su se javljali kod skupine kojima je urađena zamjena zalistaka. Kod iste skupine vrijednosti E, Hgb i Trc bile su manje nego kod ostalih skupina. Postoji povezanost troponina i hemodinamskih vrijednosti.
Abstract (english)
Objectives: To measure the differences in demographic indicators, compare the values of pulmonary and peripheral vascular resistance and the values of troponin in patients undergoing aortocoronary bypass surgery, aortic valve replacement or both surgeries. Study design. retrospective study Materials and Methods: 108 patients who underwent cardiac surgeries from 4 January 2016 to 25 May 2016 were included in the study. Disease histories and hemodynamic values of those patients were analysed. The patients were divided into three groups due to the surgical procedure they had. Demographic indicators, laboratory findings and hemodynamic values were compared in the study groups. All data were analysed using t-test and χ2 test, Fisher's exact test, ANOVA test, and Pearson's correlation. Results: The study groups did not differ by age and sex. The most common comorbidity in all groups was hypertension (94.44 %). The mean values of body mass index were greater than 29. Erythrocyte (E), haemoglobin (Hgb) and platelets (P) values were the lowest in patients undergoing valve surgery (E = 3.42, Hgb = 102.75, P = 110.34). The highest values of troponin had the group of patients who underwent both surgeries and the lowest values had the group which underwent aortocoronary bypass surgery. There is a positive correlation between troponin, pulmonary and peripheral vascular resistance, and troponin with mean pulmonary pressure. The correlation between troponin, cardiac output and stroke volume was negative (p < 0.05 for all comparisons). Conclusion: Myocardial infarction, diabetes, lipid disorders, and angina pectoris were less common in the groups that had undergone aortic valve replacement, and values of E, Hgb and P were lower than in other groups. A statistically significant correlation between troponin and hemodynamic values was observed.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:881063
Study programmeTitle: University Graduate Studies
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-07-27 11:53:08