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master's thesis
Utjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca
2017. urn:nbn:hr:152:720346
Mecanović, Ivana
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Mecanović, I. (2017). Utjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:720346

Mecanović, Ivana. "Utjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:720346

Mecanović, Ivana. "Utjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:720346

Mecanović, I. (2017). 'Utjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 02 April 2025, https://urn.nsk.hr/urn:nbn:hr:152:720346

Mecanović I. Utjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2017 [cited 2025 April 02] Available at: https://urn.nsk.hr/urn:nbn:hr:152:720346

I. Mecanović, "Utjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:152:720346

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Metadata
TitleUtjecaj citratnih inhibitora kristalizacije na stvaranje bubrežnih kamenaca
Title (english)The influence of citrate crystallisation inhibitors on the formation of kidney stones
AuthorIvana Mecanović
MentorJosip Galić (mentor)
Committee memberVatroslav Šerić (predsjednik povjerenstva)
Committee memberJerko Barbić (član povjerenstva)
Committee memberJosip Galić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2017-07-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Urology
Abstract
Cilj istraživanja: Ispitati postoji li povezanost razine citratnih inhibitora u urinu s pojavnošću kalcijskih kamenaca na način da se odrediti stupanj prezasićenja urina kalcijem u ispitanika s kalcijskom urolitijazom i usporedi s rezultatima ispitanika iz kontrolne skupine, da se odredi inhibitorni potencijal urina na temelju određivanja koncentracije citrata te da se u konačnici utvrdi utjecaj indeksa rizika kalcij citratnim omjerom na razvoj urolitijaze. Nacrt studije: Studija će biti... More ustrojena kao presječna studija iz povijesnih podataka. Ispitanici i metode: U istraživanju je sudjelovalo 97 ispitanika podijeljenih u dvije skupine. Prvu skupinu činili su ispitanici s kalcijskom urolitijazom, a drugu skupinu činili su ispitanici kod kojih nije utvrđeno stvaranje kamenaca. Promatrane varijable su: spol, dob, pH, kalcij i citrat te sastav kamenca za ispitanike s urolitijazom utvrđen metodom infracrvene spektroskopije. Rezultati: Medijan dobi ispitanika s kalcijskom urolitijazom uključenih u istraživanje je iznosio 50 godina. Glavna komponenta 52 % analiziranih kamenca je kalcij-oksalat monohidrat i ta činjenica je u pozitivnoj korelaciji s povišenom koncentracijom kalcija u urinu ovih ispitanika. Navedeno ide u prilog prezasićenosti urina kalcijem kao jednim od ključnih čimbenika koji povećavaju rizik za razvoj kalcijskih kamenaca. U istraživanju je kao indeks rizika za razvoj kamenaca u omjer stavljena koncentracija kalcija i citrata i dokazano je da je indeks veći u ispitanika s urolitijazom nego u kontrolnoj skupini. Zaključak: Ispitanici s kalcijskom urolitijazom imaju veći stupanj prezasićenja urina kalcijem, nižu koncentraciju citrata u urinu i veću vrijednost kalcij citratnog omjera. Less
Abstract (english)
Objectives: The aim of this study was to examine whether there is correlation between the citrate inhibitors levels with the presence of calcium stones in urine. The degree of calcium satiation in urine was determined in patients with calcium urolithiasis and compared with the control group in order to determine the inhibitory activity of the urine from urine citrate levels. Finally, the aim was to determine the influence of the risk index represented by the calcium citrate ratio on the... More development of urolithiasis. Study design: The study was structured as a cross-sectional study of historical data. Participants and Methods: The study included 97 respondents divided into two groups. The first group consisted of respondents with calcium urolithiasis, and the second group were respondents who did not report stone formation (control group). Variables included in the study were as follows: sex, age, pH levels, calcium and citrate levels, and the stone composition for patients suffering from urolithiasis, which was determined by infrared spectroscopy. Results: The median age of urolithiasis respondents was 50. The main component of 52 % of the analyzed stones was calcium oxalate monohydrate, which correlates to the elevated calcium urine concentration of the respondents. This fact corroborates the hypothesis that calcium satiation in urine is one of the key factors in the development of calcium stones. In the study, calcium citrate concentration ratio was considered risk factor for the development of the stones and respondents with urolithiasis were proven to have had higher risk index that the control group. Conclusion: Respondents with calcium urolithiasis have higher degree of urinary excretion of calcium, lower concentration of citrate in urine, and higher calcium citrate ratio. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:720346
Study programmeTitle: University Graduate Studies
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-08-01 12:42:15
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