Study goals. To determine the frequency of fatigue symptoms in patients with diabetes mellitus depending on the presence of polyneuropathy. To determine the incidence of restless legs syndrome and sleep disturbances in patients with diabetic polyneuropathy and the correlation of restless legs syndrome and sleep disturbances in patients with polyneuropathy on appearance and severity of fatigue. Study design. A cross-sectional study. Methods and participants. The study included patients with diabetes mellitus and diabetic polyneuropathy diagnosis, regardless of the type, who came to the Electromyurographic (EMNG) laboratory for diagnostic treatment in April 2017. The data were collected by an anonymous self-questionnaire structured for this study, consisting of demographic data, standardized Pittsburgh sleep quality scales, fatigue score scale and restless leg syndrome questionnaire. Results. Thirty subjects were included in this study, 29 of which experienced mild tiredness. The majority of subjects with fatigue symptoms had mild to moderate symptoms of restless legs (20/29). We have not found the difference in neither sleep quality and symptoms, fatigue symptoms and restless legs syndrome nor in sleep quality depending on the presence of restless leg syndrome. Correlation between the lower quality of sleep with the subjects and coffee consumption (coefficient of contingency c = 0.707, p value = 0.05) as well as the presence of fatigue with the subjects and coffee consumption (coefficient of contingency c = 0.707, p value = 0.01) was established. Conclusion. Patients with diabetic polyneuropathy tend to feel fatigue regardless of the quality of sleep and the presence of restless leg syndrome. Coffee consumption additionally disturbs the quality of sleep.