| Title | Promjene debljine makule nakon operacije katarakte mjerene optičkom koherentnom tomografijom |
| Author | Hrvoje Bradvica |
| Mentor(s) | Suzana Matić (thesis advisor)
|
| Abstract | Cilj istraživanja: Cilj istraživanja je ispitati promjenu debljine makule optičkom koherentnom tomografijom prije i nakon ultrazvučne fakoemulzifikacije te otkriti povezanost s intraoperativnim varijablama fakoemulzifikacije – ukupnom disipiranom energijom (eng. CDE) i volumenom potrošene tekućine Ustroj studije: Prospektivno kohortno istraživanje Ispitanici i metode: U istraživanje je uključeno 30 odraslih ispitanika oba spola, sukcesivno predviđenih za operaciju mrene, normalne debljine makule, koji su pristali na istraživanje. Isključni kriteriji su ranije operacije oka, postojanje ili ranija anamneza uveitisa ili makularnog edema, dijabetičari, neproliferativna i proliferativna dijabetička retinopatija, raniji argon laserski tretmani unutar tri mjeseca prije operacije, korioidalne bolesti te nemogućnost izvođenja OCT-a. Svakom će se bolesniku na dan prije ekstrakcije leće, sedam i mjesec dana nakon ugradnje leće, izmjeriti debljina makule OCT-om i vidna oštrina. Za svakog pacijenta zabilježene se vrijednosti glavnih intraoperativnih varijabli. Rezultati: Nakon operacije došlo je do značajnog poboljšanja vidne oštrine čiji je medijan prije operacije 0,25, a poslije 0,95. Fakoemulzifikacija nije imala značajan utjecaj na intraokularni tlak, medijan 16 mmHg na svim mjerenjima. Nakon 7. i 30. dana dolazi do značajnog porasta debljine makule. Medijan CDE iznosio je 9,73, a količina potrošene tekućine medijana 46 cm3, te nisu imali značajan utjecaj na debljinu makule. Zaključak: Značajno je poboljšanje vidne oštrine nakon operacije. Značajna je razlika u debljini makule prije i poslije operacije. Povećanje debljine makule ne korelira direktno s intraoperacijskim parametrima – povećani CDE i volumenom potrošene tekućine. |
| Keywords | cataract cystoid macular oedema optical coherence tomography ultrasound phacoemulsification. |
| Parallel title (English) | Macular thickness changes after cataract surgery measured by optical coherence tomography |
| Committee Members | Josip Barać (committee chairperson)
Dubravka Biuk (committee member)
Suzana Matić (committee member)
|
| Granter | Josip Juraj Strossmayer University of Osijek
Faculty of Medicine |
| Place | Osijek |
| State | Croatia |
| Scientific field, discipline, subdiscipline | BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Ophthalmology
|
| Study programme type | university |
| Study level | integrated undergraduate and graduate |
| Study programme | University Graduate Studies |
| Academic title abbreviation | dr. med. |
| Genre | master's thesis |
| Language | Croatian |
| Defense date | 2018-06-18 |
| Parallel abstract (English) | Aim: The aim of the study was to examine the changes of macular thickness measured by optical coherence tomography before and after ultrasound phacoemulsification and to determine the possible connection with intraoperative variables of phacoemulsification – cumulative dissipated energy ( CDE ) and estimated fluid used ( EFU). Study type: Prospective cohort study. Patients and methods: The study included 30 adults of both gender who successively underwent ultrasound phacoemulsification cataract surgery and who consented to the study. Exclusion criteria were previous eye surgery, diagnosis or anamnesis of uveitis or macular oedema, diabetes, non proliferative and proliferative diabetic retinopathy, earlier argon laser treatments within three months before surgery, chorioidal diseases, inability to perform an OCT. OCT macular thickness measurement and the best corrected visual accuitiy were performed on every patient a day before surgery, on7th and on 30th day after surgery. For each patient mean intraoperative variables were measured and recorded- CDE and estimated fluid used. Results: All patients had a significant increase in the best corrected visual acuity (BCVA) after phacoemusification cataract surgery (median before surgery 0,25, and after 0,95). Phacoemulsification did not have significant impact on intraocular pressure (IOP), median pressure value was 16 mmHg on all controls. After 7th and 30th day a significant increase in macular thickness has been observed, median value 244,5 and 254. Mean CDE was 9,73 (interquartile range from 8,89 to 17,48), and EFU was 46 cm3 (interquartile range from 39 cccm to 57 cccm) which did not have significant influence on macular thickness changes. Conclusion: Significant improvement in the best corected visual acuity was observed after phacoemulsification. Study has shown that there was significant difference in macular thickness before and after the surgery. However, increase in macular thickness did not directly corelate with intraoperative phaco parameters like increase in CDE and estimated fluid used. |
| Parallel keywords (Croatian) | cistoidni makularni edem katarakta optička koherentna tomografija ultrazvučna fakoemulzifikacija. |
| Resource type | text |
| Access condition | Open access |
| Terms of use |  |
| URN:NBN | https://urn.nsk.hr/urn:nbn:hr:152:046908 |
