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master's thesis
Klinička i laboratorijska dijagnostika hemofilije B
2019. urn:nbn:hr:152:358691
Pešut, Luka
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Pešut, L. (2019). Klinička i laboratorijska dijagnostika hemofilije B (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:358691

Pešut, Luka. "Klinička i laboratorijska dijagnostika hemofilije B." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:358691

Pešut, Luka. "Klinička i laboratorijska dijagnostika hemofilije B." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:358691

Pešut, L. (2019). 'Klinička i laboratorijska dijagnostika hemofilije B', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 20 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:358691

Pešut L. Klinička i laboratorijska dijagnostika hemofilije B [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2019 [cited 2024 November 20] Available at: https://urn.nsk.hr/urn:nbn:hr:152:358691

L. Pešut, "Klinička i laboratorijska dijagnostika hemofilije B", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:152:358691

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Metadata
TitleKlinička i laboratorijska dijagnostika hemofilije B
Title (english)Clinical and laboratory diagnosis of haemophilia B
AuthorLuka Pešut
MentorSilva Zupančić-Šalek (mentor)
Committee memberVatroslav Šerić (predsjednik povjerenstva)
Committee memberSanja Mandić (član povjerenstva)
Committee memberSilva Zupančić-Šalek (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2019-04-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract
Ciljevi istraživanja: istražiti povezanost vrijednosti laboratorijskih rezultata APTV - a i razine aktivnosti FIX te izgleda kliničke slike sa težinom hemofilije B. Nacrt studije: Istraživanje slučaja Ispitanici i metode: Istraživanje je provedeno na 30 muških bolesnika sa prisutnom hemoragijskom dijatezom, akutnom epizodom krvarenja bez osnovne dijagnoze ili s pozitivnom obiteljskom anamnezom na hemofiliju B. Iz plazme bolesnika provedeno je određivanje dužine APTV - a i razina aktivnosti FIX fotometrijskom metodom Rezultati: Bolesnici s težim oblikom bolesti imaju niže vrijednosti aktivnosti FIX i povišene vrijednosti APTV - a, te pokazuju prisustvo ciljnog zgloba za razliku od bolesnika sa lakšim oblikom bolesti koji imaju značajno niže vrijednosti APTV - a, više vrijednosti aktivnosti FIX i i nemaju prisutan ciljni zglob. Zaključak: Težina hemofilije B se može procijeniti laboratorijskim rezultatima APTV - a i razinom aktivnosti FIX.
Abstract (english)
Objectives: To examine interconnection of laboratory values of APTV and activity of FIX, and clinical appearance with severity of haemophilia B. Study design: Case study Participants and methods: The study was done on 30 male patients with presence of the haemorrhagic diathesis, acute bleeding without established diagnosis or presence of family anamnesis of haemophilia B. In the patients plasma, APTV and activity of FIX were determined using photometric method. Results: Patients with the severe form of disease have lower activity of FIX and higher values of APTV with presence of the target joint, while patients with the mild form have significantly higher activity of FIX and lower values of APTV without presence of the target joint. Conclusion: Severity of haemophilia B can be determined with laboratory results of APTV and activity of FIX.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:358691
Study programmeTitle: University graduate study
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra medicinsko laboratorijske dijagnostike (magistar/magistra medicinsko laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-07-08 12:39:38