Abstract | Ciljevi istraživanja: Odrediti učestalost novootkrivenog dijabetesa tipa 2 u bolesnika s preboljelim AKS-om obrađenim na Zavodu za kardiologiju KBCO-a tijekom jedne godine, ispitati razlike u vrijednostima: GUP, kreatinin, dob, pušenje, kolesterol, HDL, LDL, trigliceridi, hipertenzija, nalaz PCI-a (bez stenta, dobio stent, preporuka CABG), UZV srca (ejekcijska frakcija, sistolička funkcija, dijastolička funkcija), NT pro-BNP, odrediti razlike u ishodima tijekom hospitalizacije (maligne aritmije, srčano zatajenje, dužina hospitalizacije, smrtni ishod) te utjecaj konkomitantne terapije (statini, antihipertenzivi, acetilsalicilna kiselina, antikoagulansi) kod bolesnika s novootkrivenim dijabetesom u odnosu na one bez postavljene dijagnoze. Nacrt studije: Istraživanje parova Ispitanici i metode: Istraživanje je provedeno na 126 ispitanika, koji su hospitalizirani na Zavodu za kardiologiju na Klinici za internu medicinu KBC-a Osijek od svibnja 2018. godine do svibnja 2019. godine. Bolesnici su podijeljeni u dvije skupine, novootkriveni dijabetičari i pacijenti bez dijagnoze dijabetesa. Istraživanje smo proveli uz pomoć podataka prikupljenih iz medicinske dokumentacije pacijenata. Rezultati: Ispitanici bez dijabetesa značajno su mlađi, središnje vrijednosti (medijana) 62 godine u odnosu na ispitanike s novootkrivenim dijabetesom. Medijan duljine hospitalizacije pacijenata u skupini bez dijabetesa iznosi 5 dana (interkvartilnog raspona 4 do 6 dana), što je značajno kraće nego u skupini pacijenata s novootkrivenim dijabetesom. Pretražujući nalaze PCI-a, najveći broj pacijenata ima ugrađen stent. Zaključak: Utvrđena je statistički značajna učestalost novootkrivenog dijabetesa tipa 2 u bolesnika s preboljelim AKS-om. |
Abstract (english) | Objectives: The aim of this study was to determine the incidence of newly diagnosed type 2 diabetes in patients with pre-existing acute coronary syndrome (ACS) treated at Clinical Hospital Center Osijek, at the Department of Cardiology in one year. The research examined differences in the following parameters: GIP, creatinine, age, smoking, HDL cholesterol, LDL, triglycerides, hypertension, PCI (no stent, stent, CABG recommendation), heart ultrasound (ejection fraction, systolic function, diastolic function), NT pro-BNP. Furthermore, the study examined differences in the outcome during hospitalization (malignant arrhythmia, length of hospitalization, death) and the influence of concomitant therapy (statins, antihypertensives, acetylsalicylic acid, anticoagulants) in patients with newly diagnosed diabetes compared to those without the diabetes diagnosis. Study design: paired research Participants and Methods: The research included 126 subjects hospitalized at the Department of Cardiology at the Clinic for Internal Medicine of CHC Osijek from May 2018 to May 2019. Patients were divided into two groups, newly diagnosed diabetics and patients without the diabetes diagnosis. The research was carried out with the help of the data collected from medical records. Results: Non-diabetic patients are significantly younger, median age is 62, compared to those with newly diagnosed diabetes. The median duration of hospitalization of patients without diabetes is 5 days (interquartile range 4 to 6 days), which is significantly shorter than in the group of newly diagnosed diabetes patients. PCI findings indicate that the largest number of patients have stent. Conclusion: There is statistically significant incidence of newly diagnosed type 2 diabetes in patients with pre-existing ACS. |