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master's thesis
Citodijagnostika u programu ranog otkrivanja raka dojke
2019. urn:nbn:hr:152:042572
Pavlović, Jelena
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Pavlović, J. (2019). Citodijagnostika u programu ranog otkrivanja raka dojke (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:042572

Pavlović, Jelena. "Citodijagnostika u programu ranog otkrivanja raka dojke." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:042572

Pavlović, Jelena. "Citodijagnostika u programu ranog otkrivanja raka dojke." Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2019. https://urn.nsk.hr/urn:nbn:hr:152:042572

Pavlović, J. (2019). 'Citodijagnostika u programu ranog otkrivanja raka dojke', Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 19 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:042572

Pavlović J. Citodijagnostika u programu ranog otkrivanja raka dojke [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2019 [cited 2024 November 19] Available at: https://urn.nsk.hr/urn:nbn:hr:152:042572

J. Pavlović, "Citodijagnostika u programu ranog otkrivanja raka dojke", Master's thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:152:042572

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Metadata
TitleCitodijagnostika u programu ranog otkrivanja raka dojke
Title (english)Role of fine needle aspiration cytology in breast cancer screening
AuthorJelena Pavlović
MentorBranka Lončar (mentor)
Committee memberKsenija Marjanović (predsjednik povjerenstva)
Committee memberIvan Hećimović (član povjerenstva)
Committee memberBranka Lončar (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2019-07-18, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Clinical Cytology
Abstract
Ciljevi istraživanja: Učiniti usporedbu citološke i patohistološke dijagnoze kod ispitanica s BI-RADS 3, BI-RADS 4 i BI-RADS 5 kategorijama mamografskih nalaza te odrediti vrijednosti citologije u dijagnostici promjena u dojci otkrivenih kroz provedbu Nacionalnog programa ranog otkrivanja raka dojke u Osječko-baranjskoj županiji. Ustroj studije: Retrospektivna poredbena studija. Materijali i metode: Istraživanje je obuhvatilo 1554 ispitanice kojima je tijekom provedbe programa probira za rak dojke mamografski nalaz klasificiran BI-RADS 3, BI-RADS 4 i BI-RADS 5 kategorijom. Citološki nalazi klasificirani su u skladu s Europskim smjernicama za osiguranje kvalitete u probiru i dijagnostici raka dojke (C1 – C5) i uspoređeni s patohistološkom dijagnozom. Rezultati: Kategorije BI-RADS 3 i BI RADS 4 mamografskih nalaza učestalije su kod ispitanica s benignom bolesti dojke u odnosu na ispitanice s malignom bolesti dojke. Kategorija BI-RADS 5 učestalija je kod ispitanica s malignom bolesti dojke. Citološka kategorija C5 učestalija je kod ispitanica s dijagnosticiranom malignom bolesti dojke. Citološke kategorije C2 i C3 učestalije su kod ispitanica s dijagnosticiranom benignom bolesti dojke. Osjetljivost citologije u dijagnostici promjena u dojci otkrivenih tijekom provedbe probira za rak dojke iznosi 95 %, specifičnost 76,2 %, pozitivna prediktivna vrijednost 93,7 %, a negativna prediktivna vrijednost 80 %. Zaključak: Citološka punkcija tankom iglom pouzdana je i jednostavna metoda za dijagnostiku lezija u dojci otkrivenih tijekom provedbe probira za rak dojke. Rezultate citodijagnostike dojke nužno je promatrati u kontekstu kliničkih i slikovnih nalaza.
Abstract (english)
Objectives: The aim of this paper was to compare the cytological and pathohistological findings in patients with BI-RADS 3, BI-RADS 4 and BI-RADS 5 mammography findings and to determine the importance of cytology findings in the diagnosis of breast changes detected through the implementation of the National Breast Cancer Screening Program in Osijek - Baranja County. Study design: Retrospective comparative study. Materials and Methods: The study included 1554 respondents classified with BI-RADS 3, BI-RADS 4 and BI-RADS 5 mammography findings in the national breast cancer screening program. Cytological findings were classified according to the European guidelines for quality assurance in breast cancer screening and diagnosis (C1 – C5) and compared with pathohistological diagnosis. Results: BI-RADS 3 and BI RADS 4 categories of the mammography findings were more common in patients with benign breast disease compared to patients with malignant breast disease. BI-RADS 5 category is more frequent in patients with malignant breast disease. Category C5 is more common in patients with malignant breast disease. Categories C2 and C3 are more frequent in patients with benign breast disease. Sensitivity of breast cytology detected during the breast cancer screening program is 95 %, specificity is 76.2 %. positive predictive value is 93.7 %, and negative predictive value is 80 %. Conclusion: Fine-needle aspiration cytology is a reliable and simple method for breast lesions detected in breast cancer screening program. The results of breast cytology must be observed in the setting of clinical and imaging findings.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:042572
Study programmeTitle: University graduate study
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra medicinsko laboratorijske dijagnostike (magistar/magistra medicinsko laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-11-06 10:19:33