Objectives: The purpose of the paper is whether it is possible to apply a short-term high-salt (HS) diet to influence indicators of cerebrovascular reactivity in young healthy subjects, in response to selected physiological research stimuli (orthostatic test, hypercapnia induced by breath hold test, hypocapnia induced by hyperventilation and hyperoxia). Study Design: The study was designed as a controlled intervention study in which all subjects were subjected to the same protocol, with repeated identical measurements. Participants and methods: In the end, 27 people participated in the research (Female: 21, Male: 6, age range 19-24). Participants were on a 7-day low-salt diet (low salt LS; <2.3 g table salt/day), followed by a 7-day HS diet (>11.2 g table salt/day). After each weeks, blood and urine analyzes and anthropometric measurements were performed. Arterial blood pressure, heart rate (HR) and heart rate variability, cerebral and systemic hemodynamic parameters were recorded simultaneously with transcranial Doppler ultrasound and The Task Force® Monitor, before and after the mentioned stimuli. Results: The subjects remained normotensive during both weeks of measurement. After orthostatic changes, mean cerebral blood flow (CBF), diastolic cerebral blood flow (DCBF) and velocity time integral (VTI) values decreased in both protocols, while cerebrovascular resistance (CVR) values increased in LS and cerebral pulsatility index (CPI) during both diets. In the systemic circulation, the cardiac output (CO) increased and the total peripheral resistance (TPR) decreased. As a result of hypercapnia, CBF, VTI, DCBF and systolic cerebral blood flow (SCBF) values were significantly increased, and CVR was reduced. A significant decrease in HF was after each measure. The increase in SV is significant in LS, and in LS and HS the drop in cardiac output (CO) and the cardiac index (CI). Hypocapnia led to a decrease in cerebral perfusion pressure (CPP), CBF, VTI, DCBF, SCBF, and an increase in CVR and CPI values, as well as an increase in SF, CO and CI, and a decrease in values of systemic pressures as well as TPR and TPRI. Hyperoxia led to lower values of cerebral pressures, increased CPI, and systemic lower HR, CO and CI. The concentration of noradrenaline and vanillylmandelic acid in urine is reduced in HS. A HS diet caused an attenuation of the sympathetic response measured by low frequency/high frequency ratio and an attenuation of the baroreceptor response compared with a LS diet during orthostatic stimulation and hyperventilation. Conclusion: The results suggest that MPK in response to the orthostatic test was preserved in the HS diet, with altered cerebrovascular resistance and dampened BRS and sympathetic activity. With exeption of the increase of SV in LS after BHT, in other provocation tests there was no difference in the physiological response between the NS and VS diet. However, the sympathetic response is dampened, not only in orthostasis, but also in hyperventilation in the HS diet.