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undergraduate thesis
Značaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti
2023. urn:nbn:hr:152:820430
Klaić, Barbara
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Klaić, B. (2023). Značaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:820430

Klaić, Barbara. "Značaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2023. https://urn.nsk.hr/urn:nbn:hr:152:820430

Klaić, Barbara. "Značaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2023. https://urn.nsk.hr/urn:nbn:hr:152:820430

Klaić, B. (2023). 'Značaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 06 April 2025, https://urn.nsk.hr/urn:nbn:hr:152:820430

Klaić B. Značaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2023 [cited 2025 April 06] Available at: https://urn.nsk.hr/urn:nbn:hr:152:820430

B. Klaić, "Značaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:152:820430

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Metadata
TitleZnačaj scintigrafije dopaminskih receptora za dijagnozu Parkinsonove bolesti
Title (english)Significance of dopamine receptor scintigraphy for the diagnosis of Parkinson's disease
AuthorBarbara Klaić
MentorTomislav Kizivat (mentor)
Committee memberDarija Šnajder Mujkić (predsjednik povjerenstva)
Committee memberSvetlana Tomić (član povjerenstva)
Committee memberTomislav Kizivat (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2023-09-08, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Human Genetics, Genomics and Proteomics
Abstract
CILJEVI ISTRAŽIVANJA: Ciljevi su bili ispitati broj scintigrafija dopaminskih receptora vremenskog perioda od jedne godine učinjenih na KZZNM KBCO, izračunati udio scintigrafija kod PB-i u ukupnom broju, kao i udio različitih uputnih dijagnoza, ispitati postoji li povezanost pojave PB-i sa spolom i dobi pacijenata i lokalizacije nalaza sa spolom, ispitati postoji li povezanost tjelesne mase s aktivnosti primijenjenog radiofarmaka. NACRT STUDIJE: Presječna studija s povijesnim... More podacima. MATERIJAL I METODE: Istraživanje obuhvaća pacijente obaju spolova i svih dobnih skupina kojima je učinjena scintigrafija DR-a od siječnja 2022. do siječnja 2023. godine. Podaci relevantni za ovu studiju prikupljeni su iz arhive postojeće medicinske dokumentacije KZZNM. Scintigrafija je učinjena pomoću 123I-ioflupan radiofarmaka na uređajima Siemens e-Cam ili GE Optima, a scintigrami su obrađeni pomoću programskih sustava SyngoMI-VA50B ili Xeleris. REZULTATI: Od ukupnog broja ispitanika s učinjenom scintigrafijom DR-a, njih 97 (51,32 %) ima PB. 60,8 % pacijenata su muškarci, dok je ženskih pacijenata 39,2 %. Medijan dobi svih ispitanika je 70 godina, interkvartilnog raspona od 60 do 75 godina. U najvećem broju slučajeva (47,4 %) nalaz je pozitivan obostrano. Bolesti živčanog sustava je najčešća uputna dijagnoza. Kod 80,4 % pacijenata aktivnost primijenjenog radiofarmaka je između 3 do 3,4 mCi. ZAKLJUČAK: U ukupnom broju, udio scintigrafija DR-a kod oboljelih od PB-i iznosi 51,32 %. Analiza prikupljenih podataka nije pokazala značajne razlike u broju oboljelih s obzirom na spol i dob, u lokalizaciji nalaza u odnosu na spol ili aktivnosti radiofarmaka u odnosu na tjelesnu masu. Less
Abstract (english)
OBJECTIVES: The objectives were to examine the number of dopamine receptor scintigraphies performed at the Clinical Institute of Nuclear Medicine and Radiation Protection of KBC Osijek in the last year, to calculate the percentage of scintigraphies in patients with Parkinson's disease in the total number, as well as the percentage of different referral diagnosis, to determine the connection between patient's sex and age and Parkinson's disease occurrence, as well as the... More connection between patient's sex and the localization of findings, to determine the connection between body mass and applied radiopharmaceutical activity. STUDY DESIGN: Cross-sectional study with historical data. MATERIAL AND METHODS: The research subjects were patients of both sexes and all age groups who underwent dopamine receptor scintigraphy from January 2022 to January 2023. Relevant data were collected from the Clinical Institute of Nuclear Medicine and Radiation Protection medical records archive. Scintigraphy was performed using 123I-Ioflupane on Siemens e-Cam or GE Optima. Scintigrams were processed using SyngoMI-VA50B or Xeleris software. RESULTS: From the total number of subjects, 97 (51,32 %) patients with Parkinson's disease underwent dopamine receptor scintigraphy. 60,8 % are male patients, while 39,2 % are female. The age median of all the patients is 70 years, with interquartile range from 60 to 75 years. In most cases (47,4 %), findings localization was on both sides. Nervous system disease is the most common referral diagnosis. In 80,4 % of patients, applied radiopharmaceutical activity is between 3 and 3,4 mCi. CONCLUSION: In a total number of cases, the share of dopamine receptor scintigraphy in patients with Parkinson's disease is 51,32 %. The analysis of the obtained data didn't show a significant difference in the occurrence regarding the patient's sex and age, in findings localization regarding the sex, or radiopharmaceutical activity regarding the patient's body mass. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:820430
Study programmeTitle: University undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/ baccalaurea) medicinsko laboratorijske dijagnostike (sveučilišni/a prvostupnik/ prvostupnica (baccalaureus/ baccalaurea) medicinsko laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-12 11:19:28
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