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undergraduate thesis
Seroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih
2024. urn:nbn:hr:152:526252
Ćurić, Anita
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Ćurić, A. (2024). Seroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:526252

Ćurić, Anita. "Seroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2024. https://urn.nsk.hr/urn:nbn:hr:152:526252

Ćurić, Anita. "Seroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2024. https://urn.nsk.hr/urn:nbn:hr:152:526252

Ćurić, A. (2024). 'Seroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 22 November 2024, https://urn.nsk.hr/urn:nbn:hr:152:526252

Ćurić A. Seroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2024 [cited 2024 November 22] Available at: https://urn.nsk.hr/urn:nbn:hr:152:526252

A. Ćurić, "Seroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:152:526252

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Metadata
TitleSeroprevalencija infekcije Epstein-Barrinim virusom kod djece i odraslih
Title (english)Seroprevalence of Epstein-Barr virus infection in children and adults
AuthorAnita Ćurić
MentorDomagoj Drenjančević (mentor)
Committee memberMaja Bogdan (predsjednik povjerenstva)
Committee memberArlen Antolović-Požgain (član povjerenstva)
Committee memberDomagoj Drenjančević (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2024-09-24, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract
Cilj istraživanja: Cilj ovog istraživanja bio je ispitati seroprevalenciju EBV-a kod djece i odraslih prema dobi, spolu i serološkom profilu. Ustroj studije: Studija je ustrojena kao retrospektivno istraživanje. Ispitanici i metode: Podatci su prikupljeni od pacijenata liječenih ambulantno ili tijekom hospitalizacije čiji su uzorci poslani na mikrobiološko testiranje. Dokaz infekcije EBV-om se provodi standardnim serološkim metodama kemiluniniscentnim imunoesejom te elektrokemiluminiscentnim imunoesejom. Rezultati: Rezultati pokazuju da se seroprevalencija EBV-a povećava s porastom dobi te da je nakon 20. godine znatno veći broj pacijenata s prošlom EBV infekcijom, ali najviše pacijenata s prošlom infekcijom ima ≥ 50 godina. S obzirom na spol zabilježena je statistički značajna razlika između muškaraca i žena u akutnim fazama infekcije te je uočen veći broj žena s prošlom infekcijom. Zaključak: Seroprevalencija raste proporcionalno s dobi te je, kako dob odmiče, sve manje negativnih, a sve više ispitanika s prošlom infekcijom ili rekativacijom. Takav rezultat je i očekivan s obzirom na sva dosadašnja istraživanja o EBV-u te na činjenicu da je na svijetu 95 % ljudi barem jednom bilo u kontaktu s virusom. Djeca do 10. godine života su većinom negativna ili imaju akutnu infekciju, a najčešći razlog tome je blizak kontakt s drugom djecom tijekom igranja.
Abstract (english)
Objective of the study: The objective of this study was to determine the seroprevalence of Epstein-Barr virus (EBV) among children and adults based on age, sex, and serological profile. Study design: The study was designed as a retrospective investigation. Participants and methods: The data were collected from patients on an outpatient basis or during hospitalization. The samples were sent for microbiological testing. The evidence of the EBV infection was obtained using standard serological methods, including chemiluminescent immunoassay and electrochemiluminescent immunoassay. Results: The results showed that EBV seroprevalence increases with age. After the age of 20, there is a significantly higher number of patients with past EBV infection, with the majority of those with past infection being over 50 years old. A statistically significant difference was observed between men and women in the acute phase of infection, with a higher number of women having past infections. Conclusion: Seroprevalence increases proportionally with age, and as age progresses, there are fewer negative cases, but also more individuals with past infections or reactivations. This result was expected, given the previous research on EBV and the fact that 95 % of the world’s population has been in contact with the virus at least once. Children under the age of 10 are mostly negative or have an acute infection, likely due to close contact with other children during play.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:526252
Study programmeTitle: University undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike (sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2024-11-05 15:34:00