| Abstract | CILJEVI ISTRAŽIVANJA. Ciljevi su istraživanja ispitati dolazi li do poboljšanja varijabli spermiograma učinjenom varikocelektomijom i koje se od varijabli kako mijenjaju i u kojoj mjeri. NACRT STUDIJE. Povijesna kohortna studija. ISPITANICI I METODE. Ispitana su 22 muškarca, u dobi od 15 do 46 godina, liječena na Zavodu za urologiju KBC-a Osijek, uključena u istraživanje kriterijem podvrgnuća varikocelektomiji. Uspoređeni su spermiogrami (volumen ejakulata, koncentracija, broj, vitalnost, pokretljivost i oblik spermija) prije i poslije operativnog zahvata. Uspoređen je i broj dijagnoza spermiograma (normozoospermija, azoospermija, oligozoospermija, asthenozoospermija, oligoasthenozoospermija) prije i poslije operacije i usporedba između dviju grupa ispitanika (mlađi od 30 godina i stariji od 30 godina). REZULTATI. Broj, oblik i pokretljivost spermija, kao i koncentracija i vitalnost značajno su veći, što ukazuje na povezanost varikocelektomije i poboljšanja spermiograma. Kod bolesnika do 30 godina nakon operacije značajno je veći postotak pokretljivih spermija i spermija normalnog oblika, a prije operacije nije bilo značajne razlike, što se može pripisati boljem odgovoru mlađeg organizma na operaciju ili kraćem trajanju bolesti. Postoje i bolesnici s preoperativnom azoospermijom u kojih su nakon operacije pronađeni spermiji u ejakulatu. ZAKLJUČAK. Broj, oblik i pokretljivost spermija značajno su povećani nakon varikocelektomije u bolesnika s varikocleom kao i koncentracija i vitalnost spermija, što su glavni prediktori povećanju plodnosti postoperativno. U mlađih je bolesnika, u odnosu na starije, značajno veći broj pokretnih spermija i spermija normalnog oblika poslije operacije, dok prije operacije nije bilo značajne razlike. |
| Abstract (english) | OBJECTIVES. The objectives of this research are to examine if the sperm variables will be improved by the varicocelectomy, which of the variables will be improved, and in which way. STUDY DESIGN. Historical cohort study. PARTICIPANTS AND METHODS. 22 men were examined, aged between 15 and 46 years, who have been treated in the Department of Urology, CHC Osijek. They were included in this study because they underwent varicocelectomy. Spermiograms were compared (ejaculate volume, concentration, number, vitality, motility and morphology of spermatozoa) before and after surgical procedure. Spermigram diagnoses values were compared (normozoospermia, azoospermia, oligozoospermia, asthenozoospermia, oligoasthenozoospermia) before and after surgical procedure. Finally, all those variables were compared between two groups of patients (younger than 30 years and older than 30 years). RESULTS. Number, morphology, and motility, as well as concentration and vitality were significantly increased, which means that there is a connection between varicocelectomy and improvement in condition of sperm. There are significantly more motile and normally shaped spermatozoa in patients younger than 30 years after surgical procedure. There was no significant difference between them before the procedure, which can mean that there is a better response of a younger organism to the procedure, or that the disease lasted shorter. There are also patients with preoperative azoospermia, some of which had spermatozoa in the ejaculate after varicocelectomy. CONCLUSION. Number, morphology and motility of spermatozoa, as well as concentration and vitality are significantly increased after varicocelectomy, which are the main predictors of increased fertility after the procedure. There are significantly more motile and normally shaped spermatozoa after surgical procedure in patients younger than 30 years, than it is in patients older than 30 years; there was no significant difference between those two groups before varicocelectomy. |
