| Abstract | CILJ ISTRAŽIVANJA. Cilj je studije procijeniti potencijalne rizične čimbenike za neurorazvojna odstupanja u dojenačkoj dobi te odrediti njihovu učestalost. USTROJ STUDIJE. Presječna studija u koju su uključena djeca s neurorazvojnim poremećajima liječena na Odjelu za pedijatriju u Općoj županijskoj bolnici Požega. ISPITANICI I METODE. Ovom studijom obuhvaćeno je 115 djece s neurorazvojnim odstupanjima rođenih između 1.1.2102. i 1.1.2017. godine. Iz medicinske dokumentacije izdvojeni su podaci o obiteljskoj anamnezi, komplikacijama u trudnoći i porodu, načinu poroda, porođajnoj masi i duljini, Apgar indeksu, bolesti u novorođenačkoj dobi, nalazu UZV mozga i pridruženim kroničnim bolestima. REZULTATI. Sindrom hipotonije bio je prisutan u 33,65 %, distoni sindrom u 31,73 %, a intracerebralna krvarenja u 30,77 % novorođenčadi. Infekcije su bile prisutne u 26,92 % slučajeva, dok je najmanje ispitanika imalo hidrocefalus (5,77 %). Od rizičnih čimbenika statistički su značajne infekcije (29,79 %) i hipertenzija (14,89 %) majke te krvarenja u trudnoći (14,89 %), a od fetalnih bolesti najčešći je bio IUGR (14.89 %). U novorođenčadi čija je obiteljska anamneza bila pozitivna najzastupljenije su epilepsija (35,29 %) i kardiovaskularne bolesti (29,41 %). U trudnoći je 43,48 % ispitanica imalo komplikacije, a tijekom poroda njih 21,74 %. Medijan rodne mase novorođenčadi iznosio je 3160 grama, rodne dužine 49 centimetara Apgara 10. ZAKLJUČAK. Majke djece s neurorazvojnim odstupanjima u najvećem broju slučajeva imale su trudnoću kompliciranu infekcijom i hipertenzijom. Najčešće oboljenje novorođenčadi bio je sindrom hipotonije. Abnormalnosti ultrazvučnog nalaza u novorođenčadi s odstupanjem u neurorazvoju u najvećem broju slučajeva bilo je obostrano intrakranijsko krvarenje. |
| Abstract (english) | OBJECTIVES. The goal of the study is to evaluate potential risk factors for neurological aberrations during the infantile age, as well as to determine the rate of potential risk factors for these aberrations STUDY DESIGN. A cross study that involves children with neurodevelopmental aberrations who are treated at the Pediatrics ward of the Požega County General Hospital. PARTICIPANTS AND METHODS. The study involves 115 children with neurodevelopmental aberrations born between 1/1/2002 and 1/1/2017. The data is extracted from the medical documentation, and it involves: family medical history, complications during pregnancy and birth, the method of birth, the length and the weight of the newborn, Apgar index, potential diseases during infancy, and any associated chronic diseases RESULTS. Hypotonic syndrome was present in 33.65 %, dystonic syndrome in 31.73 %, and intracerebral hemorrhage in 30.77 % of the newborns. Infections were present in 26.92 % of the cases, while the fewest infants had hydrocephalus (5.77 %). Out of all the risk factors involved, the most statistically significant ones are infections (29.79 %) and hypertension (14.89 %) of the mother and vaginal bleeding during pregnancy (14.89 %), and out of diseases during the fetal period, the most common was IUGR (14.89 %). The family history showed that the most common risk factor is epilepsy (35.29 %) and cardiovascular diseases (29.41 %). During the pregnancy, 41.61 % of the tested mothers had complications, and complications during the birth were present in 21.74 %. The median of birth mass of the newborns was 3160 grams, and the length was set at 49 centimeter. The median of the APGAR score was 10. CONCLUSION. Mothers with neurodevelopmental abnormalities in most cases had a pregnancy complicated by infection and hypertension. The most common illness in newborns was hypotension syndrome. Out of abnormalities found on ultrasound in neonatal infants with deviation to neurodevelopment, bilateral intracranial bleeding was found in most cases. |
