prikaz prve stranice dokumenta Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze
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undergraduate thesis
Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze
2017. urn:nbn:hr:152:878970
Vidas, Patricia
Josip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek

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Vidas, P. (2017). Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek. Retrieved from https://urn.nsk.hr/urn:nbn:hr:152:878970

Vidas, Patricia. "Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:878970

Vidas, Patricia. "Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, 2017. https://urn.nsk.hr/urn:nbn:hr:152:878970

Vidas, P. (2017). 'Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, accessed 12 December 2024, https://urn.nsk.hr/urn:nbn:hr:152:878970

Vidas P. Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek; 2017 [cited 2024 December 12] Available at: https://urn.nsk.hr/urn:nbn:hr:152:878970

P. Vidas, "Potencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Faculty of Medicine Osijek, Osijek, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:152:878970

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Metadata
TitlePotencijalna primjena anti-Mullerovog hormona (AMH) kao biljega spermatogeneze
Title (english)Potential application of anti-Mullerian hormone (AMH) as a marker of spermatogenesis
AuthorPatricia Vidas
MentorSanja Mandić (mentor)
Committee memberLjubica Glavaš-Obrovac (predsjednik povjerenstva)
Committee memberVatroslav Šerić (član povjerenstva)
Committee memberSanja Mandić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Faculty of Medicine Osijek
Osijek
Defense date and country2017-09-27, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Clinical Biochemistry
Abstract
Cilj istraživanja bio je ispitati dijagnostičku važnost određivanja AMH-a u procjeni spermatogeneze. Ispitanici i metode U istraživanje je bilo uključeno 87 muških ispitanika: 12 ispitanika s azoospermijom, 11 ispitanika s oligospermijom i 64 ispitanika s normospermijom. Za istraživanje su se rabili uzorci krvi i preostali uzorci sjemene tekućine pacijenata koji su bili u postupku obrade radi ispitivanja neplodnosti zaprimljeni u Zavod za kliničku laboratorijsku dijagnostiku od ožujka do srpnja 2017. godine. U uzorcima sjemene tekućine, prema protokolu Svjetske zdravstvene organizacije (WHO, engl. World Health Organization), postupkom mikroskopske analize napravljena je analiza sjemene tekućine. AMH u serumu i sjemenoj plazmije izmjeren je kemiluminiscentnom imunokemijskom metodom (CLIA) na UniCel DXI 600 imunokemijskom analizatoru (Beckman Coulter Inc., Brea, SAD). Rezultati su obrađeni statističkim programom MedCalc verzija 12.0.0.0. (MedCalc Software, Mariakerke, Belgium). Rezultati Vrijednosti AMH-a u sjemenoj plazmi i serumu bile su niže u ispitanika s oligospermijom i azoospermijom (serum: 34,4 prema 51,2 pmol/L, P = 0,007; sjemena plazma: 3,4 prema 13,2 pmol/L, P = 0,030) u usporedbi s ispitanicima s normospermijom. Ispitivanjem Spearmanova koeficijenta korelacije utvrđeno je da između vrijednosti koncentracija AMH-a u serumu i AMH-a u sjemenoj plazmi nema korelacije. Zaključak Određivanje koncentracije AMH-a može biti korisno za dobivanje informacija o spermatogenezi u neplodnih muškaraca.
Abstract (english)
Objective: The aim of the study was to examine the diagnostic significance of AMH determination in spermatogenesis assessment. Materials and Methods: The study included 87 male subjects: 12 subjects with azoospermia, 11 subjects with oligospermia and 64 subjects with normospermia. The study used blood samples and remaining samples of semen fluid from patients who were in the process of examination for infertility testing received at the Department of Clinical Laboratory Diagnostics from March to July 2017. Microscopic analysis of semen liquid samples was made according to the World Health Organization (WHO) protocol. The AMH in serum and semen plasma was measured by chemiluminescence immunochemical method (CLIA) on the UniCel DXI 600 immunochemical analyzer (Beckman Coulter Inc., Brea, USA). The results were processed using the statistical software MedCalc version 12.0.0.0. (MedCalc Software, Mariakerke, Belgium). Results: Values of AMH in semen plasma and serum were lower among subjects with oligospermia and azoospermia (serum: 34.4 vs 51.2 pmol/L, P=0.007; semen plasma: 3.4 vs 13.2 pmol/L; P=0.030) in comparison with normospermia subjects. Examination of Spearman's correlation coefficient showed no correlation between AMH concentration in serum and AMH in semen plasma. Conclusion: Determination of AMH concentration may be useful for receiving spermatogenesis information in infertile men.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:152:878970
Study programmeTitle: University undergraduate study
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike (sveučilišni prvostupnik/prvostupnica (baccalaureus/ baccalaurea) medicinske laboratorijske dijagnostike)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2018-04-12 12:03:06