Objective: To determine the opinions of nurses of Pula General Hospital on cardiopulmonary resuscitation commencement and performance in hospitalized patients. Study design: Cross-sectional study Participants and methods: This study was conducted during the month of August, 2017. The study included 101 participants qualified as nurses employed in both intensive and non-intensive units of Pula General Hospital. For the purpose of this study a self-constructed questionnaire was used. Results: Fear of cardiopulmonary resuscitation performance was expressed by 8 (7, 9 %) participants, while the determination for cardiopulmonary resuscitation commencement was expressed by 40 (39, 6 %) participants. The need for additional resuscitation education was expressed by 52 (51, 5 %), while 54 (53, 5 %) participants expressed their desire for frequent resuscitation trainings. The cardiopulmonary resuscitation knowledge test pass mark was set to 60 %, the majority of participants, 58 (57, 4 %), failed to achieve the passing mark. Participants with higher education and those currently in the process of faculty training achieved a significantly higher knowledge rate on cardiopulmonary resuscitation (p<0, 05) compared to others. Participants who attended additional resuscitation education 1 – 2 years prior had a statistically significant (p= < 0, 0001) higher knowledge rate compared to those without any additional education and those who attended an additional education earlier than 2 years ago. There is a weak positive correlation (rho= 0,227) between participants' knowledge rate and the determination for cardiopulmonary resuscitation commencement and a statistically weak negative correlation (rho = -0,232) between participants' fear rate and determination for cardiopulmonary resuscitation commencement. Conclusion: The results of this study indicate the need for implementation of systematic additional education and evaluation of the knowledge of nurses on cardiopulmonary resuscitation procedures.