Objectives: The objectives of the research were to examine the attitudes of students from the 1st to 6th year of medical studies at the Faculty of Medicine in Osijek towards people with mental disorders, to examine whether there is a difference in attitudes towards people with mental disorder related to sociodemographic characteristics of respondents (sex, year of study, family history of psychiatric illness), and to assess the incidence of stigmatization of people with mental disorders among respondents. Study design: Cross-sectional study. Participants and Methods: A total of 200 1st to 6th year students of the integrated undergraduate and graduate study of medicine at the Faculty of Medicine in Osijek participated in this research. Respondents completed an anonymous survey questionnaire. The first part of the questionnaire contains data on gender, age, year of study, psychiatric illness, and the existence of psychiatric illness in the immediate family. The second part contains the questionnaire about the students’ attitudes towards people with mental disorders taken with MICA-2 scale (Mental Illness: Clinicians’ Attitudes Scale). Results: More positive attitudes are noticed in respondents whose family member has suffered or is suffering from psychiatric illness. There is no significant difference in attitudes towards people with mental disorders among respondents depending on gender and the year of study. Also, there is no significant difference in attitudes towards people with mental disorders depending on whether the respondents suffer from some psychiatric illness or not. Conclusion: Medical students at the Faculty of Medicine in Osijek show a tendency to stigmatize people with mental disorders. More positive attitudes towards people with mental disorders were observed in respondents whose family member has suffered or is suffering from a psychiatric illness.