Objectives: The study aimed to examine the prevalence of pain syndrome in participants with focal cervical dystonia, to differentiate the pain syndrome type and severity as well as its effect on the quality of life of participants with focal cervical dystonia. Study Design: Cross-sectional study. Participants and Methods: The sample comprised 48 patients with diagnosed cervical dystonia who are receiving treatment at the Botulinum Toxin Outpatient Clinic at the Neurology Department at the University Hospital in Osijek. The research included a questionnaire through which participants reported their age, gender, duration and type of cervical dystonia, pain severity, the description, localization and presence of pain, analgesic use and type. Pain severity was reported by way of a VAS scale. Quality of life was assessed by way of an SF-36 questionnaire. Motor symptom severity was evaluated by way of the Tsui score. Results: Pain syndrome was present in 83 % of participants with focal cervical dystonia. The most frequently reported pain types included tightness, cramping, and pressure. The pain was localized predominantly in the posterior neck and head region, and the shoulders. No correlation was observed between pain syndrome and age, motor symptom severity, duration and type of cervical dystonia. While not impacted by motor symptom severity, quality of life components are affected adversely by pain severity. The results demonstrate that the presence of pain affects quality of life most significantly in the domains of physical and social functioning, physical limitations, and physical pain. Conclusion: In patients with cervical dystonia, pain syndrome was found to decrease quality of life to a greater extent than motor symptom severity.