Objectives: The main objective of this study was to determine the frequency of perioperative myocardial infarction in patients treated at the Clinical department of Cardiac Surgery, Department of Surgery and Neurosurgery of University Hospital Center Osijek, Croatia trough years 2011 and 2012. Study Design: Retrospective analysis of medical records. Methods: Cardiac troponin I was used as the most important indicator for myocardial infarction diagnosis, which is the most severe form of ischemic heart disease, and main cause of mortality in urban countries. As a criteria for diagnosis of perioperative myocardial infarction level of cardiac troponin I higher than 3.5 μg/L was used. All the patients included in this study, were operated for revascularization of a myocardia without the extracorporeal circulation machine. Results: Out of 69 patients included in this study, 20 of them had perioperative myocardial infarction, which makes a quota of 29 %. The results obtained in this study show that there is not statistically significant correlation between perioperative myocardial infarction and hypertension, age, sex, obesity and dyslipidemia. Correlation analysis indicated that there is a statistically significant minor positive correlation between obesity and hypertension (r = 0.26), obesity and diabetes (r = 0.25) and between hypertension and diabetes (r = 0.29). Chi-squared test did not show statistically significant differences between risk factors and perioperative myocardial infarction. Conclusion: The most common risk factors observed in this study did not show a significant correlation with perioperative myocardial infarction. That can be explained with the fact that the studied group was relatively small, and high-risk patients were more prevalent.