Objective: The main objective of the research was to determine whether there are any differences in patterns of sleep disturbance between patients with Parkinson's disease and focal dystonia, which suggests that etiopathogenesis is the same or a different disturbance. Study design: Cross-sectional study. Participants and methods: The research included 32 patients diagnosed with Parkinson's disease and 26 patients diagnosed with focal dystonia hospitalized at the Clinic of Neurology, Clinical Hospital Center Osijek. As a research tool, the socio-demographic survey, the Pitts5*-burgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Short Form Health Survey-36 (SF-36), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI – II) were used. Results: Most of the patients in both groups did not significantly differ in sociodemographic characteristics, comorbidity, associated habits, presence of anxiety and depression. The only differences were in age distribution and in taking therapy. Sleep disturbances analyzed by PSQI showed a poorer quality of sleep in 78% of Parkinson's and 65% of patients with focal dystonia, while excessive daily fatigue was more expressed in Parkinson's disease patients but did not show pathological significance in both groups. Sleep latency was significantly longer in patients with focal dystonia (p <0.006). In both groups, sleep disturbances had a negative impact on the quality of life. Conclusion: Sleep disturbances were common in both groups of patients. Patients with focal dystonia had severe problems with falling asleep. Excessive daily fatigue disturbances are more commonly reported in Parkinson's disease patients. There is a negative link between the overall PSQI and ESS results for both groups of patients and the quality of health.