Aim: The aim of this study was to investigate opinions towards cardiopulmonary resuscitation (CPR) and patient monitoring as well as working conditions among nurses employed in Clinical Hospital Centre Osijek. Subjects and methods: The study included 182 nurses employed in Clinical Hospital Centre Osijek. The majority of them work at Clinical Department of Surgery and Clinical Department of Internal Medicine. The research instrument was a structured questionnaire, specially designed for this study. Results: Total scale score for items regarding cardiopulmonary resuscitation (CPR) and patient monitoring showed different results according to education level. The score was higher in nurses who have secondary vocational school diploma (P=0.04). The median was higher in nurses working at Clinical Department of Surgery, Clinical Department of Internal Medicine and Department of Urology (4 (3-4)). The results showed differences regarding cardiopulmonary resuscitation and patient monitoring among younger nurses with less work experience and those who have not attended a course for cardiopulmonary resuscitation (median 4, interquartile range 3-4, minimum and maximum 1-5). There was no difference in average scale score regarding working conditions according to sex (P=0.59), education level (P=0.44), age (P=0.24), work experience (P=0.48) and attendance of CPR courses (P=0.99). Conclusion: The scale results showed that nurses have positive opinion towards cardiopulmonary resuscitation (CPR) and patient monitoring. Nurses who have secondary vocational school diploma have more positive opinion towards cardiopulmonary resuscitation (CPR) and patient monitoring. Younger nurses with less work experience and those who have not attended a course for cardiopulmonary resuscitation express different opinions towards cardiopulmonary resuscitation (CPR) and patient monitoring.