The objectives of this research were to establish the frequency of analgesic use for relieving menstrual pain, study mood changes related to the use of analgesics and examine the possible occurrence of psychological addiction to analgesics. The research was conducted as a cross-sectional study. The participants were 130 female students of the University of Josip Juraj Strossmayer Osijek. The data were collected by using an anonymous questionnaire which included questions about demographic characteristics, habits related to the use of analgesics, mood changes during menstrual pain and mood changes related to the use of analgesics. The questionnaire also included 4 questions which represented an adjusted CAGE questionnaire to evaluate clinical signs of addiction to analgesics. All P values were two-sided and the level of significance was set at 0.05. According to the results, it was found that the prevalence of dysmenorrhea was 87.7% and that 90% of the participants used analgesics to relieve the menstrual pain. It was concluded that the use of analgesics depended on the intensity of the pain and that most of the participants used analgesics in case when the pain was severe and not subsiding. The pain subsided completely in 57.3% of the participants, whereas the rest claimed that the pain was still present but easier to bear. The results indicated mood changes during menstrual pain in 64.6% of the participants and the fact that most of the participants felt better after the use of analgesics. In case there was no access to analgesics, 60.8% of the participants felt worse. Regarding the access to analgesics, it was established that most of the participants did not consult their doctor about dysmenorrhea and, at the same time, used analgesics that were not prescribed by a physician. The results of the CAGE questionnaire did not show any single case which could confirm clinical indications to analgesic addiction.