OBJECTIVES: The aim of this study was to investigate the effect of smoking before and after septoplasty and septorinoplasty on the increasingly important quality of life (Qol). Septoplasty and septorinoplasty are among the most commonly performed surgeries for patients with nasal obstruction but are also performed for aesthetic reasons. STUDY DESIGN: cross-sectional study PARTICIPANTS AND METHODS: The research was conducted at the Clinic for otorhinolaryngology and surgery of the head and neck of the Clinical Hospital Center Osijek (CHCO), from January 2018 to June 2018. 26 patients were included, and two groups were formed: a group of 14 non-smokers and a group of 12 smokers. All of the patients were diagnosed with nasal septum deformity and underwent septoplasty and septorinoplasty. Computerized rhinomanometry was used for obtaining the data on total nasal resistance and flow, and a subjective assessment of the severity of symptoms was obtained using SNOT 22. RESULTS: Data obtained using SNOT 22 showed a reduction in the severity of symptoms after the surgery. Rhinomanometry has shown a significant improvement in the nose airflow and a reduction in nasal resistance after septoplasty and septorinoplasty. There was no statistically significant difference in the incidence and severity of 22 offered symptoms, or in values of overall resistance and air flow, between the non-smoker group and the smoker group. CONCLUSION: Septoplasty and septorinoplasty are improving the quality of life without the significant difference between non-smokers and smokers.