Objectives: The aim of this paper was to determine the percentage of the patients who suffer from cardiac disease, but do not take the prescribed therapy. Furthermore, the aim was to determine whether there is correlation between atrial fibrillation (AF) and stroke in Osijek-Baranja County, and to determine how many patients have risk factors to develop stroke. Study design: The research was carried out as across-cutting study based on historical data. Participants and methods: The study included patients from Unified Emergency Hospital Admission Centre and the Clinic for Neurology at the University Hospital Centre Osijek, in Osijek, who were hospitalised at the Clinic for Neurology because they suffered stroke, or they were in risk of developing one. Anamnestic data was taken from each patient individually (gender, age, employment information, cardiac disease history, regular therapy, diagnostic methods and the results of diagnostic methods). Results: Out of a total of 200 patients who suffered stroke, 73 (36.7%) of them had ischemic stroke, and 15 (7.5%) had haemorrhagic stroke. AF is the most common cause of ischemic stroke. In this research, 23 (23.7%) patients had AF and developed stroke. Cardiovascular disease was diagnosed in 181 (92.5%) patients, whichemphasises the correlation with strokes. Cardiac therapy is one of the most important factors in stroke prevention. There were 151 (87.3 %) patients who took antihypertensive therapy, and 51 (25.5%) who took Andol® as a preventive therapy. Conclusion: There are more patients who developed ischemic stroke, than those who developed hemorrhagic stroke. AF is one of the leading causes of stroke.