Objectives: The aim of this study was to evaluate the success rate of anterior cervical discectomy and fusion (ACDF) with standolone CAGE and allograft in the cervical intervertebral space by comparing clinical features before and after the surgical procedure. Success rate is defined by a reduction in pain intensity in the neck and arm using the VAS scale before and after the procedure. Study outline: The study was set up as a retrospective-prospective study. It included 16 patients, 9 of whom were women, and 7 men. Participants and methods: Data from medical history obtained from medical records of the Department of Orthopaedic Surgery, University Hospital Center Osijek, was used for research purposes. The data collected was used to evaluate the success of surgical method of ACDF with standalone CAGE and allograft. The analyzed data included gender, age, affected intervertebral disc level, number of used CAGEs, CAGE thickness, pain evaluation in the arms and neck using VAS scale before and after surgery, duration of dysphasia, fusion, CAGE migration. Results: The median age of patients at the time of surgery was 44 years. The most commonly affected 13/ 16 intervertebral disc level was C5. The least affected 3/ 16 intervertebral disc level was C3. The difference in pain intensity in the neck and arms before and after the procedure was statistically significant and it supports the efficiency of the procedure. The median duration of dysphasia was 3 weeks. Fusion was accomplished in all of the participants. None of the participants has experienced the CAGE migration. Conclusion: A significant reduction of pain was achieved in the treatment of cervical radiculopathy with ACDF with standalone CAGE and allograft. Key words: allograft; ACDF; standalone CAGE; cervical radiculopathy